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Making the Cut with CRISPR-Cas9©

Making the Cut with CRISPR-Cas9©

SKU: MCC
S$254.00Price
Excluding Sales Tax

Model how the Cas9 protein is programmed with RNA to search for and identify specific sequences of DNA before making the double-stranded cut. Explore and discuss how Cas9 is being engineered with new features that make it a useful tool for editing the human genome. With the kit's colorful foam pieces and placemat your students can:

 

  • Build a schematic model of the CRISPR-Cas9 RNA-guided endonuclease.
  • Understand how the protein binds to a specific sequence of double-stranded DNA - and cuts it.
  • Demonstrate how that cut destroys viral genome and prevents the infection of bacteria.
  • And much more!

 

CONTENTS:

1 - GROUP SET CONTENT:

1 Foldable Placemat*

6 White sticky-back Cas9 parts

2 White Nuclease parts

5 Orange tracr RNA pieces

1 Black Spacer RNA piece

40 Red Adenine (A) DNA Nucleotides

40 Yellow Thymine (T) DNA Nucleotides

40 Green Guanine (G) DNA Nucleotides

40 Blue Cytosine (C) DNA Nucleotides

40 Purple RNA Nucleotides (10 each of A, U, G & C)

40 Tan RNA Nucleotides (10 each of A, U, G & C)

40 Blue RNA Nucleotides (10 each of A, U, G & C)

1 Gray Tetraloop

1 Gray Cytosine Deanimase

 

*Placemat may be folded in half (printing out) before applying the sticky-back foam to make storage in the box easier. Or leave the placemat flat and store outside of box. See Assembly Instructions for more information.

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